Case Study & Report

A palatal swelling transpires out as a nasal B-cell Non-Hodgkin’s Lymphoma

Authors: Sunil Pazhayanur Venkateswaran, Rafiq Abdul Karim Vasiwala, Norfadzilah Mohd Yusof.

ABSTRACT

Primary sinonasal Non-Hodgkin’s Lymphoma’s (NHLs) are quite rare and emulate the presentation of benign inflammatory diseases. It is challenging to distinguish them morphologically and radiologically from other malignant neoplasms. We report a 37-year-old male patient who presented with obstruction of the nasal passages, rhinorrhoea, epistaxis, post nasal drip, facial swelling, orbital symptoms and pyrexia. The mass was a nasal diffuse large B-cell lymphoma confirmed by immunohistochemistry. After the first cycle of chemotherapy was started, the patient improved with resolution of the facial swelling, pain and visual defects. A high index of suspicion is required to differentiate sinonasal lymphomas from other lesions.

Keywords: Diffuse large B-cell lymphoma, palate, CD20, CD79α, and KI-67.

Citation: IeJSME 2018 12(2): 22-25

DOI: https://doi.org/10.56026/imu.12.2.22